Friday, March 29, 2024

A Commercial Space Story I Haven't Been Covering

I've been remiss in providing details on the Varda orbital experiments that recently concluded with a successful recovery of their payload that - much like OSIRIS-REx's samples - parachuted into the Utah desert in February. It's an important milestone and mission.

This story has been going on, quietly and in the background, for years. Varda Space launched their small satellite on the Falcon 9 Transporter-8 rideshare mission on June 12, 2023. They had actually thought they could return their payload by mid July of '23, but had to wait for government approval - which is what delayed them until this past February. 

Considering the time it takes to design a mission, design and build the satellite and acquire a ride into space, you'd think the FAA had time to think about this mission and clear the reentry, but they were apparently afraid. You see, the Varda W-1 capsule was autonomously manufacturing complex pharmaceutical molecules that are hard to create on Earth because of gravity. Doing the manufacturing in space should allow chemicals like this to be manufactured efficiently and at lower costs than on the ground.

In a July 24 interview, Delian Asparouhov, co-founder of Varda, said the company was still working with the Federal Aviation Administration’s Office of Commercial Space Transportation for a reentry license for the spacecraft. That office, best known for licensing commercial launches, is also responsible for overseeing reentries by commercial spacecraft.

A key issue, he said, is that Varda is the first to seek a reentry license under new FAA regulations known as Part 450. Those regulations were enacted by the FAA more than two years ago to streamline the launch and reentry licensing process.

“I think a lot of the collaborations that we’ve had with the FAA have been trailblazing, and we recognize that, given we’re the first, we set the standard for what future Part 450 reentry looks like,” he said. Varda started discussions with the FAA in early 2021, shortly after the company’s founding.

They received the license in early February and performed the re-entry and recovery on February 21. By March 20, the company revealed that everything worked and released a preprint paper (pdf alert) of their results.

The W-1 mission sought to test the feasibility of making therapeutics in space, testing Varda's hardware off Earth for the first time. During its time in orbit, the W-1 capsule successfully crystalized the metastable Form III of the antiviral drug ritonavir, which then survived its return to Earth. The space-processed ritonavir has since been analyzed, and per an X post by Varda Space cofounder Delian Asparouhov, "[t]hem space drugs cooked real good."

While pharmaceuticals have been processed in microgravity on parabolic flights and the International Space Station, Varda Space's method aims to be more efficient and cost-effective, using uncrewed capsules that serve dual purposes as a mini-factory and a reentry vehicle.

I bet when more Fed Bois read that line starting with, "Them space drugs..." they might want to have Varda followed a little more closely. Wish I was kidding.

Varda Space's manufacturing capsule is examined by recovery personnel as it sits on the desert floor of the Utah Test and Training Range on Feb. 21, 2024. (Image credit: Varda Space/John Kraus)



4 comments:

  1. I'm reasonably sure that if any almighty Fed Agency has a problem with this (triggered by the word "drugs"), they're a certified, farking bunch of idiots.

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  2. Interesting, SiG. The comparability studies between the two products would be interesting, especially if for some reason the "manufactured in space" was more pure. This could conceivably make it an entirely different compound and thus necessitate a new submission and new studies.

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